Linkage Disequilibrium (D)

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Calculate LD between two loci

Formula

D = P_AB - P_A × P_B

Compare two scenarios side-by-side

Freq AB Haplotype

Freq Allele A

Freq Allele B

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D_max

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About This Calculator & Guide

About the Linkage Disequilibrium (D)

The Linkage Disequilibrium (D) is a dedicated tool in our Biology category designed to help you calculate ld between two loci in seconds. By automating the underlying mathematics, this utility eliminates manual calculations and provides reliable, instantaneous estimations.

Mathematical Principles & Calculation Steps

To compute the results, the calculation engine processes your custom inputs: Freq AB Haplotype, Freq Allele A, Freq Allele B. Specifically, the calculations are evaluated using the standard relationship: D = P_AB - P_A × P_B. All computations are performed locally within your secure browser session, ensuring absolute data privacy and instantaneous updates without any network delay.

Worked Step-by-Step Calculation Example

Worked Example Sandbox

For illustrative purposes, consider the following calculation using our default values. When we initialize the input fields with Freq AB Haplotype = 0.5, Freq Allele A = 0.6, Freq Allele B = 0.7, the client-side calculator processes the numbers to resolve the formula and produce the final outputs: D = 0.08 and D_max = 0.12 and D' = 0.667.

How to Use This Calculator

Set Inputs: Adjust the input values: Freq AB Haplotype, Freq Allele A, Freq Allele B to match your scenario.
Verify Outputs: The outputs: D, D_max, D' are updated in real-time on your screen.
Iterate: Change values and compare alternative scenarios to find your optimal result.

Frequently Asked Questions

What does the Linkage Disequilibrium (D) calculator do?+

Calculate LD between two loci It is part of the Biology category on WebCalcSys and provides instant, accurate results. Simply enter your values and the calculator computes the answer in real time — no downloads or sign-ups required.

How do I use the Linkage Disequilibrium (D) calculator?+

Enter the required values (Freq AB Haplotype, Freq Allele A, Freq Allele B) into the input fields. The calculator processes your data instantly and displays D, D_max, D' in real time. You can adjust any input to run what-if scenarios.

What formula does the Linkage Disequilibrium (D) calculator use?+

This calculator uses the formula: D = P_AB - P_A × P_B. It is based on standard biology principles and is trusted by students, professionals, and educators worldwide.