Creatinine Clearance (Cockcroft-Gault)
Estimate creatinine clearance (CrCl) — a measure of kidney function — using the Cockcroft-Gault equation. Essential for drug dosing in patients with renal impairment.
Creatinine Clearance (Cockcroft-Gault)
intermediateEstimate creatinine clearance for renal function assessment
Formula
CrCl = [(140-age)×wt]/(72×Cr) × 0.85 if female
Scenario A
How It Works
The Cockcroft-Gault equation estimates creatinine clearance based on serum creatinine, age, weight, and sex:
CrCl (mL/min) = ((140 − Age) × Weight) / (72 × Serum Cr)
For females: multiply result by 0.85
Interpretation: Normal CrCl: 90-120 mL/min. Mild impairment: 60-89. Moderate: 30-59. Severe: 15-29. Kidney failure: <15.
Example
A 50-year-old man weighing 70 kg with serum creatinine 1.0 mg/dL:
CrCl = ((140-50) × 70) / (72 × 1.0)
CrCl = (90 × 70) / 72 = 87.5 mL/min
This indicates mildly reduced kidney function (Stage 2 CKD).
Frequently Asked Questions
What is the difference between CrCl and eGFR?
Both estimate kidney function. CrCl (Cockcroft-Gault) overestimates GFR slightly and is still widely used for drug dosing. eGFR (MDRD/CKD-EPI) is more accurate for chronic kidney disease staging.
When should I adjust drug doses based on CrCl?
Many drugs require dose adjustment when CrCl falls below 50 mL/min, especially renally eliminated drugs (antibiotics, antidiabetics, anticoagulants). Always consult drug-specific guidelines.
Save Configuration Snapshot
Save current parameters to your dashboard for instant one-click reloading.
About This Calculator & Guide
About the Creatinine Clearance (Cockcroft-Gault) Calculator
The Creatinine Clearance (Cockcroft-Gault) Calculator is a specialized online utility designed to help you estimate creatinine clearance using the cockcroft-gault equation for renal function assessment. free online crcl calculator. It performs calculations in real-time to provide immediate, reliable estimates for study, work, or daily tasks.
How to Use
Simply enter your parameters in the input fields of the calculator widget above. The tool evaluates the inputs instantly and displays the results in real-time. You can modify any value to check alternate scenarios and compare figures dynamically.
Data Privacy & Safety
All calculations are executed locally within your web browser. No inputs are sent to our servers or stored externally, ensuring your personal and financial details remain completely private and secure.
FAQ
Frequently Asked Questions
What does the Creatinine Clearance (Cockcroft-Gault) Calculator do?+
Estimate creatinine clearance using the Cockcroft-Gault equation for renal function assessment. Free online CrCl calculator. It is designed for quick everyday use and gives clear results without requiring a sign in.
Is the Creatinine Clearance (Cockcroft-Gault) Calculator free to use?+
Yes. The Creatinine Clearance (Cockcroft-Gault) Calculator is free to use online and works directly in your browser.
Can I use the Creatinine Clearance (Cockcroft-Gault) Calculator on mobile?+
Yes. The calculator layout is responsive, so you can use it on phones, tablets, laptops, and desktop screens.